Uniquely identifiable characteristics
Distinguishing Feature : the dense but short spike of long and thin purple flowers and the few, small, paired leaves on the stem. Leaves have convex teeth and are rounded at the tip.
There is only one plant under the Betonica Genus, Betony, which is native and found in grasslands, hedgebanks, heaths, sometimes in large but loose groups. It avoids heavy soils such as with clay, but is common in England and Wales, but only locally in Jersey and extremely local in Scotland and Ireland. On cliff tops it is often very short.
USE BY BUTTERFLIES
|LAYS EGGS ON
Trigonelline, Stachydrine and Betonine, Betonicine and Choline are all alkaloids found within Betony. They are all called 'Betaines', a type of Zwitterion where a nitrogen or phosphorus atom has a positive charge. The negative counterpart is seldom shown - it could be any negative ion, usually the chloride ion since common salt, NaCl, is a ubiquitous source.
Choline Chloride is an example of a betaine with chlorine as the negative ion.
Trigonelline (N-methylnicotinic Acid, or Nicotinic acid betaine), is found not only in Betony, but also in
Garden Peas, Hemp seeds,
Oats, Coffee and Potatos amongst a few other plants. Trigonelline in coffee is said to impart coffee with some anti-oxidative properties and contribute to its aroma and slightly bitter taste. Trigonelline is also produced within the human body as a result of the metabolism of niacin (Vitamin B3 aka
Nicotinic Acid), after which it is excreted in urine.
Stachydrine is also present also in Yarrow, Motherwort, Alfalfa
Chrysanthemum and Citrus plants. It is the betaine of L-Proline, and is also known as Proline Betaine. It is an osmoprotectant capable of helping organisms to survive extreme osmotic stress, such as the bacterium E. coli when it finds itself in harsh environments such as in the urine of mammals. The bacterium uptakes the stachydrine from the environment it is in with the help of various internal transport mechanisms. Your Author can find no evidence that Stachydrine is present in plants of the genus Stachys, such as Hedge Woundwort (Stachys sylvatica) to which Betony once belonged.
Structurally, Betonine is almost identical to Stachydrine, but with an additional hydroxyl group attached to the ring.
Betaine itself is a non-proteinogenic amino acid (NPAA) which can masquerade as an amino acid in the human body and become wrongly incorporated into proteins, which then might not function correctly. But because of great confusion between betaine and 'a betaine' the Betaine shown above is now generally referred to as
N,N,N-TrimethylGlycine, and is the betaine originally found in
Beet (Beta vulgaris) from which it derives its name.
Choline is just the cation (the part of the ion with positive charge). It can be paired up with any negative ion, but usually this is the chloride ion, making Choline Chloride.
Acetyl Choline is another important molecule with the Choline backbone, and is usually found as the chloride, Acetylcholine Chloride. Choline is an essential nutrient for mammals and is usually grouped as belonging to the B-complex vitamins.
Betony is also said to contain a series of
Betonyoside A to
Betonyoside F plus
Acetoside. Other phenolic compounds include
Campneosides, Forsythoside B,
Leucosceptoside and Tannins.
Shown above is just one of the six PhenylEthanoid Glycosides,
Betonyoside F which is found in Betony. The moieties in red are glycosides, two differing 6-membered sugars and one of a 5-membered pentose.
However, he has found two newly discovered Iridoid Glycosides which Betony contains, one a diglycoside called
Allobetonicaside (which contains the sugar
6-O-AcetylMioporoside as well several already known Iridoid Glycosides, Acetylharpagide, Harpagide, Harpagoside and
Several Terpenoids such as Linalool,
Terpinene, the sesquiterpenoids
Cadinol, and Caryophyllene plus the diterpenoids
Betonicolide and the glycoside
Betonycoside B, (which are not to be confused with the PhenylEthanoid Glycosides mentioned above with a very similar name!).
As can be seen, the diterpenoid glycoside
Betonycoside B displayed immediately above is very different to the PhenylEthanoid Glycoside shown higher up. What a difference a 'c' makes...